Potency of a vaccine prepared from A/swine/Hokkaido/2/1981 (H1N1) against A/Narita/1/2009 (H1N1) pandemic influenza virus strain
Identifieur interne : 000851 ( Main/Exploration ); précédent : 000850; suivant : 000852Potency of a vaccine prepared from A/swine/Hokkaido/2/1981 (H1N1) against A/Narita/1/2009 (H1N1) pandemic influenza virus strain
Auteurs : Masatoshi Okamatsu [Japon] ; Yoshihiro Sakoda [Japon] ; Takahiro Hiono [Japon] ; Naoki Yamamoto [Japon] ; Hiroshi Kida [Japon]Source :
- Virology Journal [ 1743-422X ] ; 2013.
Abstract
The pandemic 2009 (H1N1) influenza virus has spread throughout the world and is now causing seasonal influenza. To prepare for the emergence of pandemic influenza, we have established a library of virus strains isolated from birds, pigs, and humans in global surveillance studies.
Inactivated whole virus particle (WV) and ether-split (ES) vaccines were prepared from an influenza virus strain, A/swine/Hokkaido/2/1981 (H1N1), from the library and from A/Narita/1/2009 (H1N1) pandemic strain. Each of the vaccines was injected subcutaneously into mice and their potencies were evaluated by challenge with A/Narita/1/2009 (H1N1) virus strain in mice.
A/swine/Hokkaido/2/81 (H1N1), which was isolated from the lung of a diseased piglet, was selected on the basis of their antigenicity and growth capacity in embryonated chicken eggs. Two injections of the WV vaccine induced an immune response in mice, decreasing the impact of disease caused by the challenge with A/Narita/1/2009 (H1N1), as did the vaccine prepared from the homologous strain.
The WV vaccine prepared from an influenza virus in the library is useful as an emergency vaccine in the early phase of pandemic influenza.
Url:
DOI: 10.1186/1743-422X-10-47
PubMed: 23384324
PubMed Central: 3571931
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000601
- to stream Pmc, to step Curation: 000601
- to stream Pmc, to step Checkpoint: 000586
- to stream Ncbi, to step Merge: 000871
- to stream Ncbi, to step Curation: 000871
- to stream Ncbi, to step Checkpoint: 000871
- to stream Main, to step Merge: 000852
- to stream Main, to step Curation: 000851
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Potency of a vaccine prepared from A/swine/Hokkaido/2/1981 (H1N1) against A/Narita/1/2009 (H1N1) pandemic influenza virus strain</title><author><name sortKey="Okamatsu, Masatoshi" sort="Okamatsu, Masatoshi" uniqKey="Okamatsu M" first="Masatoshi" last="Okamatsu">Masatoshi Okamatsu</name><affiliation wicri:level="1"><nlm:aff id="I1">Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818</wicri:regionArea><wicri:noRegion>Sapporo 060-0818</wicri:noRegion></affiliation></author><author><name sortKey="Sakoda, Yoshihiro" sort="Sakoda, Yoshihiro" uniqKey="Sakoda Y" first="Yoshihiro" last="Sakoda">Yoshihiro Sakoda</name><affiliation wicri:level="1"><nlm:aff id="I1">Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818</wicri:regionArea><wicri:noRegion>Sapporo 060-0818</wicri:noRegion></affiliation></author><author><name sortKey="Hiono, Takahiro" sort="Hiono, Takahiro" uniqKey="Hiono T" first="Takahiro" last="Hiono">Takahiro Hiono</name><affiliation wicri:level="1"><nlm:aff id="I1">Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818</wicri:regionArea><wicri:noRegion>Sapporo 060-0818</wicri:noRegion></affiliation></author><author><name sortKey="Yamamoto, Naoki" sort="Yamamoto, Naoki" uniqKey="Yamamoto N" first="Naoki" last="Yamamoto">Naoki Yamamoto</name><affiliation wicri:level="1"><nlm:aff id="I1">Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818</wicri:regionArea><wicri:noRegion>Sapporo 060-0818</wicri:noRegion></affiliation></author><author><name sortKey="Kida, Hiroshi" sort="Kida, Hiroshi" uniqKey="Kida H" first="Hiroshi" last="Kida">Hiroshi Kida</name><affiliation wicri:level="1"><nlm:aff id="I1">Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818</wicri:regionArea><wicri:noRegion>Sapporo 060-0818</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I2">Research Center of Zoonosis Control, Hokkaido University, Sapporo, 001-0020, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Research Center of Zoonosis Control, Hokkaido University, Sapporo, 001-0020</wicri:regionArea><wicri:noRegion>001-0020</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23384324</idno><idno type="pmc">3571931</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571931</idno><idno type="RBID">PMC:3571931</idno><idno type="doi">10.1186/1743-422X-10-47</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">000601</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000601</idno><idno type="wicri:Area/Pmc/Curation">000601</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000601</idno><idno type="wicri:Area/Pmc/Checkpoint">000586</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000586</idno><idno type="wicri:Area/Ncbi/Merge">000871</idno><idno type="wicri:Area/Ncbi/Curation">000871</idno><idno type="wicri:Area/Ncbi/Checkpoint">000871</idno><idno type="wicri:Area/Main/Merge">000852</idno><idno type="wicri:Area/Main/Curation">000851</idno><idno type="wicri:Area/Main/Exploration">000851</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Potency of a vaccine prepared from A/swine/Hokkaido/2/1981 (H1N1) against A/Narita/1/2009 (H1N1) pandemic influenza virus strain</title><author><name sortKey="Okamatsu, Masatoshi" sort="Okamatsu, Masatoshi" uniqKey="Okamatsu M" first="Masatoshi" last="Okamatsu">Masatoshi Okamatsu</name><affiliation wicri:level="1"><nlm:aff id="I1">Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818</wicri:regionArea><wicri:noRegion>Sapporo 060-0818</wicri:noRegion></affiliation></author><author><name sortKey="Sakoda, Yoshihiro" sort="Sakoda, Yoshihiro" uniqKey="Sakoda Y" first="Yoshihiro" last="Sakoda">Yoshihiro Sakoda</name><affiliation wicri:level="1"><nlm:aff id="I1">Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818</wicri:regionArea><wicri:noRegion>Sapporo 060-0818</wicri:noRegion></affiliation></author><author><name sortKey="Hiono, Takahiro" sort="Hiono, Takahiro" uniqKey="Hiono T" first="Takahiro" last="Hiono">Takahiro Hiono</name><affiliation wicri:level="1"><nlm:aff id="I1">Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818</wicri:regionArea><wicri:noRegion>Sapporo 060-0818</wicri:noRegion></affiliation></author><author><name sortKey="Yamamoto, Naoki" sort="Yamamoto, Naoki" uniqKey="Yamamoto N" first="Naoki" last="Yamamoto">Naoki Yamamoto</name><affiliation wicri:level="1"><nlm:aff id="I1">Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818</wicri:regionArea><wicri:noRegion>Sapporo 060-0818</wicri:noRegion></affiliation></author><author><name sortKey="Kida, Hiroshi" sort="Kida, Hiroshi" uniqKey="Kida H" first="Hiroshi" last="Kida">Hiroshi Kida</name><affiliation wicri:level="1"><nlm:aff id="I1">Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818</wicri:regionArea><wicri:noRegion>Sapporo 060-0818</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I2">Research Center of Zoonosis Control, Hokkaido University, Sapporo, 001-0020, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Research Center of Zoonosis Control, Hokkaido University, Sapporo, 001-0020</wicri:regionArea><wicri:noRegion>001-0020</wicri:noRegion></affiliation></author></analytic><series><title level="j">Virology Journal</title><idno type="eISSN">1743-422X</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>The pandemic 2009 (H1N1) influenza virus has spread throughout the world and is now causing seasonal influenza. To prepare for the emergence of pandemic influenza, we have established a library of virus strains isolated from birds, pigs, and humans in global surveillance studies.</p></sec><sec><title>Methods</title><p>Inactivated whole virus particle (WV) and ether-split (ES) vaccines were prepared from an influenza virus strain, A/swine/Hokkaido/2/1981 (H1N1), from the library and from A/Narita/1/2009 (H1N1) pandemic strain. Each of the vaccines was injected subcutaneously into mice and their potencies were evaluated by challenge with A/Narita/1/2009 (H1N1) virus strain in mice.</p></sec><sec><title>Results</title><p>A/swine/Hokkaido/2/81 (H1N1), which was isolated from the lung of a diseased piglet, was selected on the basis of their antigenicity and growth capacity in embryonated chicken eggs. Two injections of the WV vaccine induced an immune response in mice, decreasing the impact of disease caused by the challenge with A/Narita/1/2009 (H1N1), as did the vaccine prepared from the homologous strain.</p></sec><sec><title>Conclusion</title><p>The WV vaccine prepared from an influenza virus in the library is useful as an emergency vaccine in the early phase of pandemic influenza.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Dawood, Fs" uniqKey="Dawood F">FS Dawood</name></author><author><name sortKey="Jain, S" uniqKey="Jain S">S Jain</name></author><author><name sortKey="Finelli, L" uniqKey="Finelli L">L Finelli</name></author><author><name sortKey="Shaw, Mw" uniqKey="Shaw M">MW Shaw</name></author><author><name sortKey="Lindstrom, S" uniqKey="Lindstrom S">S Lindstrom</name></author><author><name sortKey="Garten, Rj" uniqKey="Garten R">RJ Garten</name></author><author><name sortKey="Gubareva, Lv" uniqKey="Gubareva L">LV Gubareva</name></author><author><name sortKey="Xu, X" uniqKey="Xu X">X Xu</name></author><author><name sortKey="Bridges, Cb" uniqKey="Bridges C">CB Bridges</name></author><author><name sortKey="Uyeki, Tm" uniqKey="Uyeki T">TM Uyeki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Garten, Rj" uniqKey="Garten R">RJ Garten</name></author><author><name sortKey="Davis, Ct" uniqKey="Davis C">CT Davis</name></author><author><name sortKey="Russell, Ca" uniqKey="Russell C">CA Russell</name></author><author><name sortKey="Shu, B" uniqKey="Shu B">B Shu</name></author><author><name sortKey="Lindstrom, S" uniqKey="Lindstrom S">S Lindstrom</name></author><author><name sortKey="Balish, A" uniqKey="Balish A">A Balish</name></author><author><name sortKey="Sessions, Wm" uniqKey="Sessions W">WM Sessions</name></author><author><name sortKey="Xu, X" uniqKey="Xu X">X Xu</name></author><author><name sortKey="Skepner, E" uniqKey="Skepner E">E Skepner</name></author><author><name sortKey="Deyde, V" uniqKey="Deyde V">V Deyde</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smith, Gj" uniqKey="Smith G">GJ Smith</name></author><author><name sortKey="Vijaykrishna, D" uniqKey="Vijaykrishna D">D Vijaykrishna</name></author><author><name sortKey="Bahl, J" uniqKey="Bahl J">J Bahl</name></author><author><name sortKey="Lycett, Sj" uniqKey="Lycett S">SJ Lycett</name></author><author><name sortKey="Worobey, M" uniqKey="Worobey M">M Worobey</name></author><author><name sortKey="Pybus, Og" uniqKey="Pybus O">OG Pybus</name></author><author><name sortKey="Ma, Sk" uniqKey="Ma S">SK Ma</name></author><author><name sortKey="Cheung, Cl" uniqKey="Cheung C">CL Cheung</name></author><author><name sortKey="Raghwani, J" uniqKey="Raghwani J">J Raghwani</name></author><author><name sortKey="Bhatt, S" uniqKey="Bhatt S">S Bhatt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hancock, K" uniqKey="Hancock K">K Hancock</name></author><author><name sortKey="Veguilla, V" uniqKey="Veguilla V">V Veguilla</name></author><author><name sortKey="Lu, X" uniqKey="Lu X">X Lu</name></author><author><name sortKey="Zhong, W" uniqKey="Zhong W">W Zhong</name></author><author><name sortKey="Butler, En" uniqKey="Butler E">EN Butler</name></author><author><name sortKey="Sun, H" uniqKey="Sun H">H Sun</name></author><author><name sortKey="Liu, F" uniqKey="Liu F">F Liu</name></author><author><name sortKey="Dong, L" uniqKey="Dong L">L Dong</name></author><author><name sortKey="Devos, Jr" uniqKey="Devos J">JR DeVos</name></author><author><name sortKey="Gargiullo, Pm" uniqKey="Gargiullo P">PM Gargiullo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Greenberg, Me" uniqKey="Greenberg M">ME Greenberg</name></author><author><name sortKey="Lai, Mh" uniqKey="Lai M">MH Lai</name></author><author><name sortKey="Hartel, Gf" uniqKey="Hartel G">GF Hartel</name></author><author><name sortKey="Wichems, Ch" uniqKey="Wichems C">CH Wichems</name></author><author><name sortKey="Gittleson, C" uniqKey="Gittleson C">C Gittleson</name></author><author><name sortKey="Bennet, J" uniqKey="Bennet J">J Bennet</name></author><author><name sortKey="Dawson, G" uniqKey="Dawson G">G Dawson</name></author><author><name sortKey="Hu, W" uniqKey="Hu W">W Hu</name></author><author><name sortKey="Leggio, C" uniqKey="Leggio C">C Leggio</name></author><author><name sortKey="Washington, D" uniqKey="Washington D">D Washington</name></author><author><name sortKey="Basser, Rl" uniqKey="Basser R">RL Basser</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wanitchang, A" uniqKey="Wanitchang A">A Wanitchang</name></author><author><name sortKey="Kramyu, J" uniqKey="Kramyu J">J Kramyu</name></author><author><name sortKey="Jongkaewwattana, A" uniqKey="Jongkaewwattana A">A Jongkaewwattana</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yasuda, J" uniqKey="Yasuda J">J Yasuda</name></author><author><name sortKey="Shortridge, Kf" uniqKey="Shortridge K">KF Shortridge</name></author><author><name sortKey="Shimizu, Y" uniqKey="Shimizu Y">Y Shimizu</name></author><author><name sortKey="Kida, H" uniqKey="Kida H">H Kida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kida, H" uniqKey="Kida H">H Kida</name></author><author><name sortKey="Ito, T" uniqKey="Ito T">T Ito</name></author><author><name sortKey="Yasuda, J" uniqKey="Yasuda J">J Yasuda</name></author><author><name sortKey="Shimizu, Y" uniqKey="Shimizu Y">Y Shimizu</name></author><author><name sortKey="Itakura, C" uniqKey="Itakura C">C Itakura</name></author><author><name sortKey="Shortridge, Kf" uniqKey="Shortridge K">KF Shortridge</name></author><author><name sortKey="Kawaoka, Y" uniqKey="Kawaoka Y">Y Kawaoka</name></author><author><name sortKey="Webster, Rg" uniqKey="Webster R">RG Webster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kida, H" uniqKey="Kida H">H Kida</name></author><author><name sortKey="Shortridge, Kf" uniqKey="Shortridge K">KF Shortridge</name></author><author><name sortKey="Webster, Rg" uniqKey="Webster R">RG Webster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kida, H" uniqKey="Kida H">H Kida</name></author><author><name sortKey="Kawaoka, Y" uniqKey="Kawaoka Y">Y Kawaoka</name></author><author><name sortKey="Naeve, Cw" uniqKey="Naeve C">CW Naeve</name></author><author><name sortKey="Webster, Rg" uniqKey="Webster R">RG Webster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kida, H" uniqKey="Kida H">H Kida</name></author><author><name sortKey="Yanagawa, R" uniqKey="Yanagawa R">R Yanagawa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Okazaki, K" uniqKey="Okazaki K">K Okazaki</name></author><author><name sortKey="Takada, A" uniqKey="Takada A">A Takada</name></author><author><name sortKey="Ito, T" uniqKey="Ito T">T Ito</name></author><author><name sortKey="Imai, M" uniqKey="Imai M">M Imai</name></author><author><name sortKey="Takakuwa, H" uniqKey="Takakuwa H">H Takakuwa</name></author><author><name sortKey="Hatta, M" uniqKey="Hatta M">M Hatta</name></author><author><name sortKey="Ozaki, H" uniqKey="Ozaki H">H Ozaki</name></author><author><name sortKey="Tanizaki, T" uniqKey="Tanizaki T">T Tanizaki</name></author><author><name sortKey="Nagano, T" uniqKey="Nagano T">T Nagano</name></author><author><name sortKey="Ninomiya, A" uniqKey="Ninomiya A">A Ninomiya</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Manzoor, R" uniqKey="Manzoor R">R Manzoor</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y Sakoda</name></author><author><name sortKey="Mweene, A" uniqKey="Mweene A">A Mweene</name></author><author><name sortKey="Tsuda, Y" uniqKey="Tsuda Y">Y Tsuda</name></author><author><name sortKey="Kishida, N" uniqKey="Kishida N">N Kishida</name></author><author><name sortKey="Bai, Gr" uniqKey="Bai G">GR Bai</name></author><author><name sortKey="Kameyama, K" uniqKey="Kameyama K">K Kameyama</name></author><author><name sortKey="Isoda, N" uniqKey="Isoda N">N Isoda</name></author><author><name sortKey="Soda, K" uniqKey="Soda K">K Soda</name></author><author><name sortKey="Naito, M" uniqKey="Naito M">M Naito</name></author><author><name sortKey="Kida, H" uniqKey="Kida H">H Kida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kida, H" uniqKey="Kida H">H Kida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kida, H" uniqKey="Kida H">H Kida</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y Sakoda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gerdil, C" uniqKey="Gerdil C">C Gerdil</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lu, B" uniqKey="Lu B">B Lu</name></author><author><name sortKey="Zhou, H" uniqKey="Zhou H">H Zhou</name></author><author><name sortKey="Chan, W" uniqKey="Chan W">W Chan</name></author><author><name sortKey="Kemble, G" uniqKey="Kemble G">G Kemble</name></author><author><name sortKey="Jin, H" uniqKey="Jin H">H Jin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kodihalli, S" uniqKey="Kodihalli S">S Kodihalli</name></author><author><name sortKey="Justewicz, Dm" uniqKey="Justewicz D">DM Justewicz</name></author><author><name sortKey="Gubareva, Lv" uniqKey="Gubareva L">LV Gubareva</name></author><author><name sortKey="Webster, Rg" uniqKey="Webster R">RG Webster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Webster, Rg" uniqKey="Webster R">RG Webster</name></author><author><name sortKey="Bean, Wj" uniqKey="Bean W">WJ Bean</name></author><author><name sortKey="Gorman, Ot" uniqKey="Gorman O">OT Gorman</name></author><author><name sortKey="Chambers, Tm" uniqKey="Chambers T">TM Chambers</name></author><author><name sortKey="Kawaoka, Y" uniqKey="Kawaoka Y">Y Kawaoka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hovden, Ao" uniqKey="Hovden A">AO Hovden</name></author><author><name sortKey="Cox, Rj" uniqKey="Cox R">RJ Cox</name></author><author><name sortKey="Haaheim, Lr" uniqKey="Haaheim L">LR Haaheim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hagenaars, N" uniqKey="Hagenaars N">N Hagenaars</name></author><author><name sortKey="Mastrobattista, E" uniqKey="Mastrobattista E">E Mastrobattista</name></author><author><name sortKey="Glansbeek, H" uniqKey="Glansbeek H">H Glansbeek</name></author><author><name sortKey="Heldens, J" uniqKey="Heldens J">J Heldens</name></author><author><name sortKey="Van Den Bosch, H" uniqKey="Van Den Bosch H">H van den Bosch</name></author><author><name sortKey="Schijns, V" uniqKey="Schijns V">V Schijns</name></author><author><name sortKey="Betbeder, D" uniqKey="Betbeder D">D Betbeder</name></author><author><name sortKey="Vromans, H" uniqKey="Vromans H">H Vromans</name></author><author><name sortKey="Jiskoot, W" uniqKey="Jiskoot W">W Jiskoot</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Koyama, S" uniqKey="Koyama S">S Koyama</name></author><author><name sortKey="Aoshi, T" uniqKey="Aoshi T">T Aoshi</name></author><author><name sortKey="Tanimoto, T" uniqKey="Tanimoto T">T Tanimoto</name></author><author><name sortKey="Kumagai, Y" uniqKey="Kumagai Y">Y Kumagai</name></author><author><name sortKey="Kobiyama, K" uniqKey="Kobiyama K">K Kobiyama</name></author><author><name sortKey="Tougan, T" uniqKey="Tougan T">T Tougan</name></author><author><name sortKey="Sakurai, K" uniqKey="Sakurai K">K Sakurai</name></author><author><name sortKey="Coban, C" uniqKey="Coban C">C Coban</name></author><author><name sortKey="Horii, T" uniqKey="Horii T">T Horii</name></author><author><name sortKey="Akira, S" uniqKey="Akira S">S Akira</name></author><author><name sortKey="Ishii, Kj" uniqKey="Ishii K">KJ Ishii</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Itoh, Y" uniqKey="Itoh Y">Y Itoh</name></author><author><name sortKey="Ozaki, H" uniqKey="Ozaki H">H Ozaki</name></author><author><name sortKey="Tsuchiya, H" uniqKey="Tsuchiya H">H Tsuchiya</name></author><author><name sortKey="Okamoto, K" uniqKey="Okamoto K">K Okamoto</name></author><author><name sortKey="Torii, R" uniqKey="Torii R">R Torii</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y Sakoda</name></author><author><name sortKey="Kawaoka, Y" uniqKey="Kawaoka Y">Y Kawaoka</name></author><author><name sortKey="Ogasawara, K" uniqKey="Ogasawara K">K Ogasawara</name></author><author><name sortKey="Kida, H" uniqKey="Kida H">H Kida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Isoda, N" uniqKey="Isoda N">N Isoda</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y Sakoda</name></author><author><name sortKey="Kishida, N" uniqKey="Kishida N">N Kishida</name></author><author><name sortKey="Soda, K" uniqKey="Soda K">K Soda</name></author><author><name sortKey="Sakabe, S" uniqKey="Sakabe S">S Sakabe</name></author><author><name sortKey="Sakamoto, R" uniqKey="Sakamoto R">R Sakamoto</name></author><author><name sortKey="Imamura, T" uniqKey="Imamura T">T Imamura</name></author><author><name sortKey="Sakaguchi, M" uniqKey="Sakaguchi M">M Sakaguchi</name></author><author><name sortKey="Sasaki, T" uniqKey="Sasaki T">T Sasaki</name></author><author><name sortKey="Kokumai, N" uniqKey="Kokumai N">N Kokumai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Takada, A" uniqKey="Takada A">A Takada</name></author><author><name sortKey="Kuboki, N" uniqKey="Kuboki N">N Kuboki</name></author><author><name sortKey="Okazaki, K" uniqKey="Okazaki K">K Okazaki</name></author><author><name sortKey="Ninomiya, A" uniqKey="Ninomiya A">A Ninomiya</name></author><author><name sortKey="Tanaka, H" uniqKey="Tanaka H">H Tanaka</name></author><author><name sortKey="Ozaki, H" uniqKey="Ozaki H">H Ozaki</name></author><author><name sortKey="Itamura, S" uniqKey="Itamura S">S Itamura</name></author><author><name sortKey="Nishimura, H" uniqKey="Nishimura H">H Nishimura</name></author><author><name sortKey="Enami, M" uniqKey="Enami M">M Enami</name></author><author><name sortKey="Tashiro, M" uniqKey="Tashiro M">M Tashiro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sakabe, S" uniqKey="Sakabe S">S Sakabe</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y Sakoda</name></author><author><name sortKey="Haraguchi, Y" uniqKey="Haraguchi Y">Y Haraguchi</name></author><author><name sortKey="Isoda, N" uniqKey="Isoda N">N Isoda</name></author><author><name sortKey="Soda, K" uniqKey="Soda K">K Soda</name></author><author><name sortKey="Takakuwa, H" uniqKey="Takakuwa H">H Takakuwa</name></author><author><name sortKey="Saijo, K" uniqKey="Saijo K">K Saijo</name></author><author><name sortKey="Sawata, A" uniqKey="Sawata A">A Sawata</name></author><author><name sortKey="Kume, K" uniqKey="Kume K">K Kume</name></author><author><name sortKey="Hagiwara, J" uniqKey="Hagiwara J">J Hagiwara</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kashima, Y" uniqKey="Kashima Y">Y Kashima</name></author><author><name sortKey="Ikeda, M" uniqKey="Ikeda M">M Ikeda</name></author><author><name sortKey="Itoh, Y" uniqKey="Itoh Y">Y Itoh</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y Sakoda</name></author><author><name sortKey="Nagata, T" uniqKey="Nagata T">T Nagata</name></author><author><name sortKey="Miyake, T" uniqKey="Miyake T">T Miyake</name></author><author><name sortKey="Soda, K" uniqKey="Soda K">K Soda</name></author><author><name sortKey="Ozaki, H" uniqKey="Ozaki H">H Ozaki</name></author><author><name sortKey="Nakayama, M" uniqKey="Nakayama M">M Nakayama</name></author><author><name sortKey="Shibuya, H" uniqKey="Shibuya H">H Shibuya</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Itoh, Y" uniqKey="Itoh Y">Y Itoh</name></author><author><name sortKey="Ozaki, H" uniqKey="Ozaki H">H Ozaki</name></author><author><name sortKey="Ishigaki, H" uniqKey="Ishigaki H">H Ishigaki</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y Sakoda</name></author><author><name sortKey="Nagata, T" uniqKey="Nagata T">T Nagata</name></author><author><name sortKey="Soda, K" uniqKey="Soda K">K Soda</name></author><author><name sortKey="Isoda, N" uniqKey="Isoda N">N Isoda</name></author><author><name sortKey="Miyake, T" uniqKey="Miyake T">T Miyake</name></author><author><name sortKey="Ishida, H" uniqKey="Ishida H">H Ishida</name></author><author><name sortKey="Okamoto, K" uniqKey="Okamoto K">K Okamoto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Manzoor, R" uniqKey="Manzoor R">R Manzoor</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y Sakoda</name></author><author><name sortKey="Nomura, N" uniqKey="Nomura N">N Nomura</name></author><author><name sortKey="Tsuda, Y" uniqKey="Tsuda Y">Y Tsuda</name></author><author><name sortKey="Ozaki, H" uniqKey="Ozaki H">H Ozaki</name></author><author><name sortKey="Okamatsu, M" uniqKey="Okamatsu M">M Okamatsu</name></author><author><name sortKey="Kida, H" uniqKey="Kida H">H Kida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sever, Jl" uniqKey="Sever J">JL Sever</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Soda, K" uniqKey="Soda K">K Soda</name></author><author><name sortKey="Ozaki, H" uniqKey="Ozaki H">H Ozaki</name></author><author><name sortKey="Sakoda, Y" uniqKey="Sakoda Y">Y Sakoda</name></author><author><name sortKey="Isoda, N" uniqKey="Isoda N">N Isoda</name></author><author><name sortKey="Haraguchi, Y" uniqKey="Haraguchi Y">Y Haraguchi</name></author><author><name sortKey="Sakabe, S" uniqKey="Sakabe S">S Sakabe</name></author><author><name sortKey="Kuboki, N" uniqKey="Kuboki N">N Kuboki</name></author><author><name sortKey="Kishida, N" uniqKey="Kishida N">N Kishida</name></author><author><name sortKey="Takada, A" uniqKey="Takada A">A Takada</name></author><author><name sortKey="Kida, H" uniqKey="Kida H">H Kida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kida, H" uniqKey="Kida H">H Kida</name></author><author><name sortKey="Brown, Le" uniqKey="Brown L">LE Brown</name></author><author><name sortKey="Webster, Rg" uniqKey="Webster R">RG Webster</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Japon</li></country></list><tree><country name="Japon"><noRegion><name sortKey="Okamatsu, Masatoshi" sort="Okamatsu, Masatoshi" uniqKey="Okamatsu M" first="Masatoshi" last="Okamatsu">Masatoshi Okamatsu</name></noRegion><name sortKey="Hiono, Takahiro" sort="Hiono, Takahiro" uniqKey="Hiono T" first="Takahiro" last="Hiono">Takahiro Hiono</name><name sortKey="Kida, Hiroshi" sort="Kida, Hiroshi" uniqKey="Kida H" first="Hiroshi" last="Kida">Hiroshi Kida</name><name sortKey="Kida, Hiroshi" sort="Kida, Hiroshi" uniqKey="Kida H" first="Hiroshi" last="Kida">Hiroshi Kida</name><name sortKey="Sakoda, Yoshihiro" sort="Sakoda, Yoshihiro" uniqKey="Sakoda Y" first="Yoshihiro" last="Sakoda">Yoshihiro Sakoda</name><name sortKey="Yamamoto, Naoki" sort="Yamamoto, Naoki" uniqKey="Yamamoto N" first="Naoki" last="Yamamoto">Naoki Yamamoto</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000851 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000851 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= H2N2V1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:3571931
|texte= Potency of a vaccine prepared from A/swine/Hokkaido/2/1981 (H1N1) against A/Narita/1/2009 (H1N1) pandemic influenza virus strain
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:23384324" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a H2N2V1
| This area was generated with Dilib version V0.6.33. |  |